发挥多学科协作优势实现肿瘤综合治疗.pdf

发挥多学科协作优发挥多学科协作优势，实现肿瘤的势，实现肿瘤的综合治疗综合治疗肿瘤治疗进入多学科综合治疗和精准医疗的时代PresidentBarackObama,StateoftheUnionAddress,January20,2015“Tonight,I’mlaunchinganewPrecisionMedicineInitiativetobringusclosertocuringdiseaseslikecanceranddiabetes—andtogiveallofusaccesstothepersonalizedinformationweneedtokeepourselvesandourfamilieshealthier.”—什么是精准医疗?WhatisPricisionMedicine?2015-6-19FrancisS.Collins,M.D.,Ph.D.,andHaroldVarmus,M.D.ANewInitiativeonPrecisionMedicine精准医疗的创新和实践Definition定义—preventionandtreatmentstrategiesthattakeindividualvariabilityintoaccount基于每个个体的基因差异而进行的个体化治疗才是有效的，也更有效率，因而称为精准医学。正如要根据一个人的身高和胖瘦来量体裁衣才能制作出合身的衣服一样。癌症是当前人类健康的最大敌人癌症是当前人类健康的最大敌人每年全世界约有600万人被癌症夺去生命我国约130万人死于癌症癌症也是可以控制的什么是MDT？MultidisciplinaryTeamTodescribeatreatmentplanningapproachorteamthatincludesanumberofdoctorsandotherhealthcareprofessionalswhoareexpertsindifferentspecialties(disciplines).Incancertreatment,theprimarydisciplinesaremedicaloncology(treatmentwithdrugs),surgicaloncology(treatmentwithsurgery),andradiationoncology(treatmentwithradiation).世界上许多癌症中心都采用了MDTFoxChasesurgeonsworkasateamwithmedicalandradiationoncologiststoofferpatientseverypossibletreatmentoption.Theteamalsoincludesgastroenterologists,pathologistsandradiologists.Together,theyassurethemostprecisediagnosisandstagingofthecancertodeterminetheneedforadditionaltreatment.Whencolorectalcancerhasprogressedbeyondtheearlieststages,thetreatmentplanusuallyincludesfollow-upchemotherapyandnewtargetedapproachesthatcancontributetolong-termsurvivalandcure.CancerManagement:AMultidisciplinaryApproach:Medical,Surgical,andRadiationOncologyRichardPazdur,LawrenceR.Coia,WilliamJ.Hoskins肿从1960年到2005年常见肿瘤的常规治疗中可以看出，综合治疗已使很多瘤的治愈率有了相当提高美国国立癌症研究所（NCI）、美国癌...